Fulham striker Andrew Johnson could be in line for his first league start since January.
Midfielders Simon Davies and Danny Murphy both hope to return from injury.
Wigan captain Gary Caldwell played 90 minutes against Swansea in midweek and may make his first league appearance of the season.
Defender Steven Gohouri could return from a calf problem, but James McCarthy (ankle) and Emmerson Boyce (hamstring) are definitely out.
Fulham
Doubtful: Davies (ankle), Murphy (groin)
Injured: Duff, Kelly & Senderos (all calf), Etuhu (ankle), Zamora (leg)
Wigan
Doubtful: Gohouri (calf)
Injured: Boyce (hamstring), McCarthy (ankle), Pollitt (elbow)